most glass colors contain LEAD, not very freindly to the human body. I wont mention arsenic or other toxic metals.
glass formulas are full of many hazardous materials, glass itself is basicaly harmless until you return it to powders, then it becomes very very dangerous, imagine what is going on while polishing, you arent removing solid chunks.
I dont think I need to mention the hazards of polishing compounds at this point, the glass itself is enough.
I work glass for a living, call it inside information if you will, I never polish or grind without a respirator and protective clothing, find the MSDS for the compounds, it may convince you to do the same.