Some bags are where pretty much all the value is. A very hard to find Vitro bag with common conquerors in it? Don't open!
In general I'd try really hard to not open most bags. Easier now that I've been doing this awhile than when I was starting out. I do have a few Japanese cat's eye bags still intact.
But I bought an Anacortes Vitro bag to be educated. And even if I can't find another, I don't mind that I took the marbles out to get some clear photos of them.
Basically my advice is to put the bag in a safe container and wait until you are sure about it.
Remember, even though you might say, "I'll just remove these staples and I can put it back together," it's easier said than done to reassemble. And if it's "I'll just make a small hole in the bag," well that's not undoable.